LONI Resource Executive Summary

Principal Investigator:
Arthur W. Toga

Co-PI:
Paul Thompson

Laboratory of Neuro Imaging
UCLA School of Medicine
Department of Neurology
635 Charles E. Young Drive South
Suite 225
Los Angeles, CA 90095-7334
Tel: 310-206-2101
Fax: 310-206-5518


Research Emphasis

The following four core research projects form a well-integrated program to characterize, measure and model both static and dynamic patterns of structural and functional changes in brain. Our research program is centered on the fundamental recognition that anatomy is not static.


Core Research
Image Processing

The Image Processing and Segmentation project is developing novel, well-validated approaches to brain image segmentation, structure analysis, and combined volume and surface registration.

Morphometry

The Deformation Morphometry and Registration project is focused on creating a powerful approach to detect and analyze longitudinal changes in the living brain.

Atlasing

The Atlasing project deals with the general problem of creating statistical maps of data from populations of subjects.

Informatics

The scope of the Informatics Project is divided into three components: data management, processing workflow and visualization.

Co-Investigators:
Richard Leahy
Roger Woods
David Shattuck
John Van Horn

Resource Capabilities
Compute Resources

Rapid advancements in imaging technology have provided researchers with the ability to produce very high-resolution, time-varying, multi-dimensional data sets of the human brain. The complexity of the new data, however, requires immense computing and storage capabilities. Institutions and scientists worldwide rely on the LONI Resource's computing resources to conduct research.

Storage

The laboratory uses a fault-tolerant storage area network (SAN) to accommodate current and projected storage requirements.

LONI Image Data Archive

The LONI Image Data Archive was constructed to provide a simple, yet effective means of securely storing, searching and organizing neuroimaging data on the LONI storage network.

Education

The LONI Resource provides regular seminars, workshops and courses on advanced information technology. Building upon a mature and established Training Program in Neuroimaging, we have designed our workshops and courses to include training on the multidimensional modeling that is the focus of this Resource.

Visualization

The Scientific Visualization Core produces sophisticated scientific images and animations that illustrate the results of the algorithmic and analytic strategies employed in the core research areas and by our collaborators.