LONIR Research

The primary goal of our Resource is the continued development and refinement of a multidimensional modeling environment in which the three spatial dimensions typically used in neuroimaging and brain mapping are extended to permit their examination within the framework of changing morphology. Our modeling framework extends the static measurement of the brain to the dynamic worlds of development, maturation, aging, and pathology.

The core research of the Resource will focus on four specific areas. These four core research projects form a well-integrated program to characterize, measure and model both static and dynamic patterns of structural and functional changes in brain. Our research program is centered on the fundamental recognition that anatomy is not static.

Image Processing

The Image Processing and Segmentation project is developing novel, well-validated approaches to brain image segmentation, structure analysis, and combined volume and surface registration.

Morphometry

The Deformation Morphometry and Registration project is focused on creating a powerful approach to detect and analyze longitudinal changes in the living brain.

Atlasing

The Atlasing project deals with the general problem of creating statistical maps of data from populations of subjects.

Informatics

The scope of the Informatics Project is divided into three components: data management, processing workflow and visualization.

Research Protocols

The LONI Resource provides investigators access to the LONI research protocols in order to provide collaborators with a validated set of methods that will enable them to analyze their brain imaging data.